UVB 조사에 의한 피부손상에 전해환원수 침수가 피부면역에 미치는 영향


The bating effects on skin immunity in electrolyzed reduced water on skin injury induced by UV irradiation in hairless mice

김동희, 윤양숙, 김철수, 성재신, 이규재

피인용수 : 0(자료제공 : 네이버학술정보)



The purpose of this study was to determine the bath effect of the electrolyzed reduced water(ERW) with the properties of high pH, low oxidation reduction potential (ORP), and antioxidant on the skin injury induced by ultra violet (UV) irradiation. For this purpose, hairless mice were irradiated with UV-B to cause skin injury, and individually taken a bath in electrolyzed reduced water (experimental group) and tap water (control group) twice a day for 15 min during 2 days. We observed scoring of skin injury, hematological analysis and cytokines profile compared to the control group. We found that skin injury of the control group was more quickly recovered than that of the ERW group. In hematological results, the levels of neutrophils and monocytes were increased in control group compared to the normal group, and increased in ERW group than TW group. But, there is no differences in basophil. The level of IFN-r was significantly increased in ERW group than that of the TW group (p<0.05).
And the levels of IL-1 , IL-6, IL-10, IL12p70 and TNF- were showed a increasing tendency. But, thesβ α e parameters had no significance between the groups.


 재료 및 방법
  1. 실험 처리수
  2. 실험동물
  3. 자외선처리, 침수, 피부손상도 측정 및 혈구검사
  4. 사이토카인 분석
  5. 통계처리
 결과 및 고찰
  1. UVB에 의한 피부손상도
  2. 혈액학적 검사


  • 김동희 Dong-Heui Kim. 연세대학교 원주의과대학 환경의생물학교실
  • 윤양숙 Yang-Suk Yoon. 연세대학교 원주의과대학 환경의생물학교실
  • 김철수 Cheul-Su Kim. 연세대학교 원주의과대학 미생물학교실
  • 성재신 Jae-Shin Sung. 연세대학교 원주의과대학 환경의생물학교실
  • 이규재 Kyu-Jae Lee. 연세대학교 원주의과대학 환경의생물학교실


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