원문정보
초록
영어
Growth hormone (GH) is obligatory for growth and development. But, there is controversy on the GH effect about reproductive processes of sexual differentiation, pubertal maturation, gonadal steroidogenesis, gametogenesis and ovulation. This study was conducted to investigate the effect of GH on estrus, ovulation and embryo implantation. The results obtained were as follows. GH stimulated to increase estrus rate (p<0.05), pregnancy rate (p<0.05), and total fetus number in mice treated for superovulation. Also, the correlation between GH and steroids, E2 and P4, at peri-estrus stage/ peri-ovulation stage/ peri-implantation stage of the superovulation-induced mice was examined. Consequently, GH co-injected with PMSG especially increased P4 level (p<0.05) at peri-estrus stage of superovulationinduced mice. In conclusion, GH co-treatment in superovulation system boosted the rate of estrus, pregnancy and total fetus by increasing progesterone level at peri-estrus stage of superovulation-induced mice.
목차
INTRODUCTION
MATERIALS AND METHODS
Experimental Animals and Housing Conditions
Superovulation Treatment
GH Treatment
Estrus Evaluation
Pregnancy Evaluation
Analysis of Serum P4 and E2
Statistical Analysis
RESULTS
GH and Reproductive Traits in Superovulation-Induced Mice
GH and Serum E2 and P4 Levels in Superovulation-Induced Mice
GH and Steroids at Peri-Estrus Stage
GH and Steroids at Peri-Ovulation Stage
GH and Steroids at Peri-Implantation
Comparison of PMSG and PMGS+GH superovulation systems
GH and Fetus Number in Superovulated Mice
DISCUSSION
GH and Estrus in Superovulation-Induced Mice
GH and Pregnancy in Superovulation-Induced Mice
REFERENCES