원문정보
A Study on Antimicrobial Effects of Silver-Alginate on Propionibacterium acnes
초록
영어
This study conducted low-molecularization of alginate to maximize antimicrobial effects and examined antimicrobial effects silver-alginate which substituted Ag+ for silver(Ag, organic antimicrobial) on Propionibacterium acnes. Antimicrobial effects of silver-alginate which was substituted by Ag+ in low-molecular alginate on P. acnes was identified by MIC. As a result, it was found that low-molecular alginate(MIC = 10,000 ㎍/㎖) and silver-alginate(MIC = 200 ㎍/㎖) had more excellent antimicrobial than lavender oil and tea tree oil which are well known for excellent antimicrobial(MIC = 20,000 ㎍/㎖). Concentration according to culture time of P. acnes was examined. As a result, concentration of silver-alginate was 0.10, 0.15, 0.21, 0.31, 0.48, and 1.01 by culture time. It indicates that it significantly inhibited the growth of P. acnes compared with the control group. Also, MIC and concentration according to culture time was measured in P. acne of alginate paste made of silver-alginate solution, and antimicrobial persistence was confirmed. acnes concentration, suggesting more excellent antimicrobial and persistent antimicrobial.
목차
I. 서론
II. 연구방법
1. 은-알지네이트 제조
2. Propionibacterium acnes에 대한 항균 효과 측정 방법
III. 결과 및 고찰
1. 유기산 첨가에 따른 저분자화 알지네이트의 점도 측정
2. P. acnes의 Minimum Inhibitory Concentration(MIC)
3. P. acnes의 배양 시간에 따른 농도
4. 은-알지네이트 용액으로 제조한 마사지용 반죽(alginate paste) 의 P. acne에 대한 MIC 측정 및 배양 시죠H게 따른 농도 측정
IV. 결론
참고문헌