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In modern society to adapt to the complex is exposed to stress. Environmental po11utants, smoking, alcohol causes a variety of oxidative stress in the human body and is weighted. Free radicals inactivate enzymes, lipid oxidation, DNA metabolism, ce11 aging and is caused. These free radicals to help prevent oxidative stress-induced, which is known to act as antioxidant vitamins and antibacterial, antioxidant, immune activation, such as having physiological activity is increasing interest in natural materials. Guava and the amount of plating (Psidium guajava L.) belonging to the tropical and subtropical fruit trees in the production as the guava fruit, leaves, bark, roots, seeds are used in a11 parts of the pharmacological purposes. Orange Guava fruit contains five times more vitamin C and insulin -like guava identified ipeseoman action confirmed that the composition and its components seuteuriktinik of polyphenols (strictinin) , ahyisoseuteuriktinin Cisostrictinin) pedeonkeolrajin (pedunculagin) turned out to be three kinds. Guava leaf extract in this study to evaluate the efficacy of the antioxidant content of total polyphenols was measured and electron donating ability. Total polyphenol content of 333.1 mg / g, 38.74% of the electron donating capacity, respectively. Extracts of the general composition of carbohydrates per unit to 0.2 g/100g of heavy metals appeared was not detected.