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Biosensor Based on Distributed Bragg Reflector Photonic Crystals for the Detection of Protein A

원문정보

초록

영어

The functionalized photonic crystals of porous silicon biosensor was prepared for the application as a label-free biosensor based on distributed Bragg reflector interferometer. Prepared distributed Bragg reflector of porous silicon biosensor displayed sharp reflection in the optical reflective spectra. The mean of construction of molecular architectures on distributed Bragg reflector of porous silicon surfaces was investigated for the step-by-step binding interaction with amines, biotin, avidin, and biotinylated protein A. The subsequent introduction of avidin, and biotinylated protein A resulted in the reflectivity shifted to longer wavelengths, indicative of a change in refractive indices induced by binding of biomolecules.

목차

Abstract
 1. Introduction
 2. Experimental
  2.1. Materials and Methods
  2.2. Thermal Oxidation of DBR PSi
  2.3. Functionalization of Oxidized DBR PSi
 2.4. Instrumentation and Data Acquisition
  3.1. Fabrication and Characterization of DBR PSi Chip
  3.2. Interferometric reflectance spectra
  3.3. Characterization of the Functionalized porous silicon layer
 4. Conclusions
 References

저자정보

  • Daehyuk Jung 단국대학교 응용물리학과

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