earticle

영어

The proposed algorithm for gene prediction compares the N/3 spectral components of DNA signal with the corresponding spectrum of period-3 suppressed DNA signal. In the DNA N/3 spectrum, for the bases for which the difference between these two spectrums is within a predefined threshold level, the signal values are replaced by the difference signal of the two spectrums. This substitution suppresses the noise in the non-coding regions of N/3 spectrum, while the coding region signal values are not affected, resulting in an improved detection. Performance of this algorithm when evaluated on HMR 195 dataset, in terms of area under the ROC curve, exhibits a 5% improvement on the DFT-based spectral content measure.