earticle

영어

Fucoidan which is contained in various species of brown seaweed such as sea mustard, kombu, ecklonia cava, and etc. appears to inhibit the production of igE. That is the source of the reduced secretion of allergic mediators, for example, asthma, hay fever, allergies, dermatitis. Fucoidan is a very useful material to relieve the symptoms of allergic diseases and prevention. In this study, it is confirmed that anti-atopic lotion containing fucoidan cures the damaged hairless mice skin caused by atopic dermatitis through observing the outward appearance of the hair less mice skin and measuring the thickness of the skin induced by atopic dermatitis, which was gradually reduced, using a digimatic indicator. Through the evaluation of immunological, fucoidan suppressed the IgE and IL-4 expression, but promoted IFN-γ expression so that make a balance between Th cell that turns out to be constituted. In addition, the weight of the spleen divided by body weight, then according to T lymphocyte, IgE and IL-4 expression inhibited the ability, and IFN-γ expression were identified.