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포스터 발표 : 바이오센서 및 바이오칩

Improvement of Catalytic Activity of Enzymes by Masking Active Sites during Immobilization of Glucose Oxidase

초록

영어

The immobilized enzyme is necessary for the development of enzyme fuel cells (EFCs) which can be applied to power source of implantable devices. The main issue to be solved is the low generation of electrical power by enzyme electrode due to several problems. One of them is the possible attachment of active site of enzyme onto support materials during immobilization of enzymes, which may decrease the chances to react between substrates and enzymes, thereby decreasing power density. Here, active site of enzyme (glucose oxidase) was masked by glucose or gluconic acid to protect active site from attachment on support material during immobilization on multiwall carbon nanotube. It was found that electric power density was increased by enzyme electrode prepared by this novel immobilization method.

저자정보

  • MEIYU ZHANG Department of Chemical & Biological Engineering, Gyeongsang National University, Jinju, Korea.
  • Chang-Joon KIM Department of Chemical & Biological Engineering, Gyeongsang National University, Jinju, Korea.
  • Sung Bae KIM Department of Chemical & Biological Engineering, Gyeongsang National University, Jinju, Korea.
  • DongWoo KHANG PRC for NEBEC, School of Materials Science and Engineering, Gyeongsang National University, Jinju, Korea.
  • In Young CHUNG Department of Electronic and Communications Engineering, Kwangwoon University, Seoul, Korea.
  • Dae Hwan KIM School of Electrical Engineering, Kookmin University, Seoul, Korea.

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