earticle

영어

We developed a multi-bit biomemory chip which was consisted of recombinant azurin variants. To store the different information for memory performance, this recombinant azurin was substituted from Cu ion to various metal ions. Each metal-substituted recombinant protein is directly self-assembled onto Au surface via thiol group of thecysteine by covalent bonding. A cyclic voltammetry (CV) and an open circuit potential (OCP) indicated that recombinant azurin variants have different redox peaks and specific open circuit potential values. Using these parameters, the memory function was verified by a chronoamperometry (CA) and open circuit potential amperomemtry (OCPA). These results presented here provide a new dimension, concept and material combinantion for developing new-type memory systems with recombinant protein. Acknowledgments : This research was supported by The Nano/Bio Science &Technology Program (M10536090001-05N3609-00110) of the Ministry of Education, Science and Technology (MEST), by the Original Technology Research Program for Brain Science through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science and Technology (2009-0093907), by the Ministry of Knowledge Economy (MKE) and Korea Institute for Advancement in Technology (KIAT) through the Workforce Development Program in Strategic Technology.