earticle

영어

Mushroom has been reported in the antitumor activity, antioxidant, and immune system health, thanks to a wide range of pharmacological and medicinal herbs as β-glucan (polysaccharide) up to recent year. Herein we studied for seven species of mushrooms on the immune stimulation. Mushroom extracts combined with the seven species were collected by hot water extraction. The effects of immune and disease resistance were evaluated in mice inoculated with bacteria-induced respiratory disease. Group 1 (mushroom extract 60 ml with 60 ml tap water), group 2 (mushroom extracts 120 ml with 200 mg powder), and control (tap water 120 ml) feeds were used. Of body weight in group 2 did not show much difference. However, the total WBC count (P =0.072) and the number of neutrophils (P =0.057) tended to increase. Total number of bacteria and inflammatory cells in bronchial led to reduce the average value but was not statistically significant. Furthermore, the total number of cells in bronchial lymph node increased with increase in CD4 and CD8 ratio. The IFN-gamma and TNF-alpha for expression levels of inflammatory cytokines in bronchial lymph nodes decreased in group 2 significantly.