earticle

영어

Shiitake mushroom (Lentinus edodes) is one of the most popular edible mushrooms in Korea, Japan, and China which are used as food. Especially Lenthionine can be considered as a anti-tumor candidate. In this study, the effect of mushroom of shiitake mushroom on the increase of immune activity and disease resistance of mice inoculated with pathogenic bacteria. Control group was of powder feed dose of 200 mg, group 1 of feed powder dose of 198 mg with 2 mg mushroom powder, and group 2 with 6 mg mushroom powder and 194 mg feed powder. The diet was supplemented with 120 ml tap water and made the powder a mix. It did not change the difference in weight compared to the control group that the total number of leukocytes increased significantly (P <0.05) also increased the total blood cell count (P <0.01). Total bacteria and inflammatory cells in bronchial washing and bronchial lymph nodes reduce and the number of CD3 and CD4 percentage of the total number of cells increased. Bronchial lymph nodes in the expression levels of inflammatory cytokines IFN-gamma compared with the control group 2 was significantly reduced and TNF-alpha was tended to decrease but not statistically significant.