원문정보
초록
영어
Stauntonia hexaphylla (S. hexaphylla) is native plants which are grown in the southern districts in korea. It has been used in Chinese folk medicine as an analgesic, sedative, diuretic, etc. This study was performed to investigate the antioxidant effects of S. hexaphylla. For this purpose, S. hexaphylla was extracted by hot water (SHH). To determine the antioxidant activity of extract, 1,1-diphenyl-2-picryhydrazyl (DPPH) radical, and superoxide scavenging was examined. Also the lipid peoxidation of the extracts was determined by TBAR using a malondialdehyde (MDA). These results showed S. hexaphylla showed a strong inhibitory power on lipid peroxidation, with significant scavenging activities of radicals including singlet oxygen, superoxide anion, and DPPH. We also found that S. hexaphylla significantly suppressed H2O2-induced ROS production in cells. As a result this extract scavenged intracellular reactive oxygen species (ROS) and DPPH radical, and prevented lipid peroxidation. Therefore, S. hexaphylla deserve further study as natural antioxidants and nutraceutical