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포스터 발표 : 효소공학

A highly efficient new lipase produced by Ralstonia sp. CS274 and its potential application in biodiesel industry

초록

영어

A lipase (RL74) able to catalyze biodiesel production from Ralstonia sp. CS274, recently isolated from Kora soil, was purified to electrophoretic homogeneity. Molecular weight of RL74 was estimated to be 28,000 Da by SDS-PAGE. The activity was highest at 50-55 °C and pH 8.0-9.5 and was stable at pH 7.0-12.0 and up to 45 °C. It was resistant to oxidizing and reducing agents and the activity was enhanced by detergents. RL74 was 1,3 specific and Km and Vmax for p-nitrophenyl palmitate were 2.73±0.6 mM and 101.4 ± 1.9 mM/min mg, respectively. N-terminal amino acid sequence showed partial homology with that of Penicillium lipases. RL74 produced biodiesel more efficiently in palm oil than in soybean oil; and the production was highest at pH 8.0, at 5% methanol and at 20% water content.

저자정보

  • Seung Sik CHO Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.
  • Jin Hee PARK Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.
  • Ji Seon SEO Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.
  • Hah Young YOO Department of Chemical and Biological Engineering, Korea University, Seoul, Korea.
  • Don hee PARK Interdisciplinary Program of Graduate School for Bioenergy & Biomaterials,Chonnam National University, Gwangju 500-757, Republic of Korea.
  • Seung wook KIM Department of Chemical and Biological Engineering, Korea University, Seoul, Korea.
  • Jin cheol YOO Department of Pharmacy, College of Pharmacy, Chosun University, Gwangju 501-759, Korea.

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