earticle

논문검색

포스터 3분 스피치 : 좌장 : 김 준 형(동아대), 황 동 수(POSTECH)

Canine Nose-mimicking Bioelectronic Sensor Using Canine Olfactory Receptor and swCNT-FET

원문정보

Jong Hyun LIM, Juhun PARK, Sang Hun LEE, Seunghun HONG, Tai Hyun PARK

한국생물공학회 한국생물공학회 학술대회 2011년도 한국생물공학회 춘계학술발표대회 2011.04 pp.148-148
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

In this study, we have developed a canine nose-mimicking bioelectronic sensor to detect low concentration of hexanal, a product of lipid oxidation. For mimicking a canine nose, nanovesicles containing canine olfactory receptor, cfOR5269, were produced from host HEK293 cells expressing cfOR5269 on their surface, and then the produced nanovesicles were immobilized on swCNT-FET platform. Since swCNT-FET amplified the signal from nanovesicles, we were able to develop a highly sensitive bioelectronic nose, which has the selectivity of the canine olfactory receptor. We obtained selective signals from hexanal treatment, and the detection lim it of our sensor was 1 fM. Our selective and sensitive bioelectronic nose can be used as an alternative sensing system for canine nose.

키워드

저자정보

  • Jong Hyun LIM School of Chemical and Biological Engineering, Seoul National University, Seoul.
  • Juhun PARK School of Physics and Astronomy, Seoul National University, Seoul.
  • Sang Hun LEE School of Chemical and Biological Engineering, Seoul National University, Seoul.
  • Seunghun HONG School of Physics and Astronomy, Seoul National University, Seoul.
  • Tai Hyun PARK School of Chemical and Biological Engineering, Seoul National University, Seoul.

참고문헌

자료제공 : 네이버학술정보

    함께 이용한 논문

      ※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

      0개의 논문이 장바구니에 담겼습니다.