earticle

영어

Stem cells have become very important resources for basic research on cell replacement therapy and other medical applications. Especially, human embryonic stem (hES) cell is derived from the inner cell mass cells of early mammalian blastocyst. This cell is pluripotent and generally retain their long-term proliferative potential in an undifferentiated state. Also, hES cell can differentiate into derivatives of all three embryonic germ layers upon transfer to in vitro differentiation culture conditions or an in vivo environment. Recently, Our team established induced pluripotent stem (iPS) cell that minimizes the ethical problem associated with the use of human embryos. These cells become a powerful tool for in vitro investigation of developmental processes at both cellular and organism levels, and offer tremendous potential for clinical application as an unlimited source of cells for transplantation and tissue generation therapies. This lecture will focused on I) Establishment of hES and iPS cells II) Tansplantation of hES cell into disease animal model III) Things to do in the near future.