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연구논문

화장품 유해 독성물질 납에 대한 보중익기탕이 흰쥐의 간대사에 미치는 영향

원문정보

Bojungiki-Tang Extract affects to reduction of heavymetal pb about Cosmetics

김훈

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초록

영어

The purpose of this study about oriental herb’s affect to reduction of heavymental. Lead acetate and Bojungiki-tang(BIT) extract, a herbal restorative were treated p.o. 40mg/kg and 500mg/kg respectively and concurrently, and examined effects of metabolic enzymes of rats. 1. The value of protein concentration on lead-poisoned group showed significant increse while the group of concurrent administration with BIT showed slight decrease. 2. The value of aniline hydroxylase activities in lead-poisined group showed 32.37% of increse while the group of concurrent administration with BIT shwed 3.91% at 4th week. 3. The value of TBA-value in lead-poisoned group showed 66.7& of increse while the group of concurrent administration with BIT showed 7.72% at 4th week. 4. The value of glucose-6-phosphate activities in lead-poisoned group showed a little decrease. These results on the whole indicated that concurrent administration with BIT showed significant recovery from the toxicity in lead-treated group.

목차

ABSTRACT
 Ⅰ. 서론
 Ⅱ. 실험
  1. 실험재료 및 추출
  2. 시약 및 기기
  3. 실험동물 및 실험기간
  4. 급성독성 시험
  5. 약물 투여
  6. 검사 항목
 Ⅲ. 실험결과 및 고찰
  1. Microsomal protein 함량 변화
  2. 간 microsome 분획중의 aniline hydroxylase의 활성변화
  3. 간 microsome 분획중 과산화지질의 변화
  4. 간 glucose-60phosphatase 활성 변화
 Ⅳ. 결론
 참고문헌

저자정보

  • 김훈 Hoon Kim. 건양대학교 의료뷰티학과

참고문헌

자료제공 : 네이버학술정보

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