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논문검색

Antidiabetic Activities Analysis by Oral Glucose Tolerance Test in Rats

초록

영어

In this study, we conducted an oral glucose tolerance test (OGTT) so as to compare antidiabetic activities of general potatoes, purple-flesh potatoes, and potato pigments in rats at various concentration levels. After allowing the rats to abstain from food for 12 hours, 10%/20% general potato, purple-flesh potato, and potato extract was orally administered to rats at 100 and 500 mg/kg concentrations. The blood glucose level was measured after an hour. Then, immediately, 1.5 g/kg of sucrose was administered through the abdominal cavity and the blood glucose measured after 30, 60, 120, and 180 minutes. 20% purple-flesh potato group and 10% general potato group, both 100 and 500 mg/kg, showed a significant concentration-dependent decrease in blood glucose levels after 30 minutes. The 100 mg/kg potato pigment group also showed a statistically significant decrease after 30 minutes. In conclusion, administration of 10% general potato, 20% purple-flesh potato, and potato pigment can reduce blood glucose level in an OGTT using rats.

목차

ABSTRACT
 INTRODUCTION
 MATERIALS AND METHODS
  Materials
  Animals
  Oral Glucose Tolerance Test
  Statistical Analysis
 RESULTS
 DISCUSSION
 REFERENCES

저자정보

  • Myung-Hwa Kang Dept. of Food Science and Nutrition, Hoseo University
  • Mi-Kyeong Choi Dept. of Food and Nutrition, Kongju National University

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