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논문검색

바이오의약 및 약물전달

Anti-Angiogenic Capacity of Anthrisci Radix and Psoraleae Semen for Anti-Obesity Purpose

초록

영어

Anti-angiogenesis was carried out for investigating of anti-cancer and anti-obesity mechanism from natural products such as Anthrisci Radix, Psoraleae Semen. The formation of angiogenesis was completely inhibited by these 2 kinds of natural products. The maximum safe dose of Anthrisci Radix, Psoraleae Semen is 0.2 ppm and 10 ppm, and the fraction of these natural products also showed higher anti-angiogenic effect, F5 and F2 fraction, respectively. F5 fraction of Anthrisci Radix completely surppressed angiogenesis with incresing its dose, while F2 fraction of Psoraleae Semen inhibited angiogenesis at 10 ppm. These 2 kind of natural products will be a good anti-angiogenic substances for anti-cancer and anti-obesity.

저자정보

  • Jong Deog KIM Department of Biotechnology & Research center on Anti-Obesity and Health Care, Chonnam National University, 550-749.
  • Gyu Seung YANG Department of Biotechnology, Chonnam National University, 550-749.
  • Jin Hyuk SHIN Department of Biotechnology, Chonnam National University, 550-749.
  • Gu Yong CHA Dept. of Culture Biotechnology, Chonnam National University,550-749.
  • Hui Jin KIM Dept. of Culture Biotechnology, Chonnam National University,550-749.
  • Jae Ho HWANG Dept. of Culture Biotechnology, Chonnam National University,550-749.
  • Kyeong Ho HAN Dept. of Culture Biotechnology, Chonnam National University,550-749.
  • Hyo Jin SEO Department of Biotechnology, Chonnam National University, 550-749.
  • Min Yong KIM Dept. of Refrigeration Eng., Chonnam National University, 550-749.
  • Tai Sun SHIN Dept. of Food Science and NutritionChonnam National University, 550-749.
  • Suk Jung OH ECOBIO INC, TBI center, Kwangju, 500-757.

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