원문정보
초록
영어
Anti-angiogenesis was carried out for investigating of anti-cancer and anti-obesity mechanism from natural products such as Anthrisci Radix, Psoraleae Semen. The formation of angiogenesis was completely inhibited by these 2 kinds of natural products. The maximum safe dose of Anthrisci Radix, Psoraleae Semen is 0.2 ppm and 10 ppm, and the fraction of these natural products also showed higher anti-angiogenic effect, F5 and F2 fraction, respectively. F5 fraction of Anthrisci Radix completely surppressed angiogenesis with incresing its dose, while F2 fraction of Psoraleae Semen inhibited angiogenesis at 10 ppm. These 2 kind of natural products will be a good anti-angiogenic substances for anti-cancer and anti-obesity.