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바이오의약 및 약물전달

Preparation of selenium nanoparticles from sulfated polysaccharides or sulfated amino acids

초록

영어

In this study, selenium nanoparticles were synthesized through the redox system. Generally, selenium nanoparticles were reported a novel selenium species with a novel biological activity and low toxicity. In the present study, we demonstrated a simple method for synthesis of size-controlled selenium nanoparticles by adding sulfated polysaccharides or sulfated amino acids to the redox system of selenite and ascorbic acid.
Selenium nanoparticles were synethesized from sulfated polysaccharides such as fucoidan, ι-carrageenan, λ-carrageenan, κ-carrageenan, chondroitin sulfate sodium salt and sulfated amino acids such as L-cysteine, L-methionine. The size of selenium nanoparticles was range of 30-150nm and the average was 100nm. The size of particles decrease according as sulfated polysaccharides concentration increase from 0.1% to 3%. And selenium nanoparticles were performed the selenium content experiment and antioxidant test. The obtained products were very stable and would be used as medicine and food material.

저자정보

  • Min-Young KIM Department of Advanced Chemicals and Engineering, Chonnam Nat.Univ., KOREA.

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