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영어
The inhibition of melanin synthesis by Bambusae caulis in Taeniam extract were evaluated. The extract of Bambusae caulis with methanol increased tyrosinase inhibition in a concentration-dependent manner.
The cellular inhibitory melanogenesis was observed in B16 melanoma cells by measuring the content of melanin synthesized. The extract of Bambusae caulis inhibited the melanin synthesis not only in the cell but also extra-cellular medium. Proteome changes in melanoma treated with Bambusae caulis extract were analyzed using 2-DE. By the image analysis, 12 spots related to the melanogenesis were detected and their effects on melanin synthesis were analyzed for the profiling of related proteins.