earticle

영어

Hybrid liposomes and Quantum Dots(QD) are widely used in medical fields of science as a novel fluorescent platform. Detection of disease related molecules and targeting of tumor cells can be done using functional group attached lipid. However, current techniques to create quantum dot(QD)- encapsulated liposome are not up to date requiring a long time and expertise. Moreover, liposomes created with conventional techniques are not evenly sized. Therefore, we demonstrate an automated platform of quantum dot(QD)-encapsulated liposome using microfluidic device and spinning device in order to collaborate multiple steps as a single process. In this paper, we illustrate the concept of automated formation method of quantum dot(QD)-encapsulated liposome.
We have confirmed the properties of quantum dot(QD)- encapsulated liposome made by using microfluidic device and spinning device under fluorescent microscope, confocal laser scanning microscopy and particle analyzer. This automated formation method of quantum dot(QD)-encapsulated liposome will provide a more effective and efficient than formation method by using sonication or extruder instruments.