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바이오센서 및 바이오칩

DNA-based Multifunctional Biomemory Device Composed of ssDNA/Cu Bilayers

초록

영어

A novel DNA-based biomemory device that was comprised of self-assembled monolayers (SAM) of ssDNA/Cu heterolayers on Au electrodes was fabricated for making biomemory device. A thiol-modified single strand DNA (26 bp) was designed and immobilized on the Au electrode. The film fabrication was confirmed by surface plasmon resornance (SPR) spectroscopy and Raman spectroscopy. The redox properties of the ssDNA/Cu molecules were measured though cyclic voltammetry (CV) experiments and open circuit potential to assign the memory parameters. The open circuit potential amperometry (OCPA) provides a various memory function using these three assigned parameters. This novel DNA-based memory device gives the new-type memory system for new biochip technologies. Acknowledgments : This research was supported by the Nano/Bio science &Technology Program (M10536090001-05N3609-00110) of the Ministry of Education, Science and Technology (MEST), by the Original Technology Research Program for Brain Science through the National Research Foundation of Korea(NRF) funded by the Ministry of Education, Science and Technology (2009-0093907), and by the Ministry of Knowledge Economy (MKE) and Korea Industrial Technology Foundation (KOTEF) through the Human Resource Training Project for Strategic Technology.

저자정보

  • Taek LEE Department of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Yong-Ho CHUNG Department of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Si-Youl YOO Department of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Qi CHEN Department of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Junhong MIN College of Bionanotechnology, Kyungwon University, Seongnam 461-701.
  • Jeong-Woo CHOI Department of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.

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