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Succinic Acid Production from Marine Biomass by metabolically engineered Mannheimia succiniciproducens LPK7

초록

영어

Bio-based succinic acid production is more attractive than petrochemical process recently. Because It is expected that the independence on petroleum and carbon dioxide fixation effect during fermentation. But high production cost problem will be resolved for industrial application.
In the previous study we have demonstrated that glucose obtained from sugar cane or corn was optimal carbon source for succinic acid production in M. succiniciproducens LPK7 (knock-out: ldhA, pflB, pta-ackA). But this biomass have shortcomings such as the requirement of farmland and food problem. On the other hand, marine biomass is advantage of vast ocean area, independence of food supply. Thus we have studied the possibility of using galactose obtained from marine biomass as carbon source. When the mixture ratio of galactose to glucose was 50:50, Yield was 84%, 102% for glucose and galactose respectively. these results suggest that marine biomass is valuable source for succinic acid production by M. succiniciproducens LPK7.

저자정보

  • Changkyou JUNG Dept. of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Young Hoon OH Dept. of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Doyeon KWON Dept. of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.
  • Jinwon LEE Dept. of Chemical & Biomolecular Engineering, Sogang University, Seoul, 121-742.

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