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환경생물 및 에너지

Effects of High Pressure Extraction on Skin Immune Activities of Spirulina maxima

원문정보

Sung Ho OH, Woon Yong CHOI, Yong Chang SEO, Ji Seon KIM, Choon Geun LEE, Hyeon Yong LEE, Do Hyung KANG

한국생물공학회 한국생물공학회 학술대회 2010 추계학술대회 및 국제심포지움 2010.10 pp.220-220
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

Marine microalgae, Spirulina maxima was extracted under high pressure and low temperature conditions at 500MPa and 60℃ for 5 and 15 min. The extraction yields from 5 min and 15 min extraction were observed as 25.3(%, w/w) and 26.1(%, w/w), respectively. It was found that the extracts for 15 min extraction had better skin immune activities than that the extract for 5 min. The extract for 15 min treatment significantly reduced the expression of Prostaglandin E2(PGE2) from CCD-986sk cells and also, increased nitric oxide production from macrophage. Prostaglandin E2(PGE2) production from UV-induced human skin cells was also greatly decreased down to 483 pg/ml in adding 1.0 mg/ml of the extract for 15 min treatment. The secretion of NO- from macrophage showed 23.8 μΜ, which was higher than process for 5 min as 19.8 μΜ. In conclusion, the most significant finding in this study was that S. maxima extracts under high pressure and low temperature process could have better skin immune activities, possibly by less damages of the components and higher extraction of active substances.

키워드

저자정보

  • Sung Ho OH Dept. of Biomaterials Engineering College of Bioscience and Biotechnology, Kangwon National University, Chunchon 200-701.
  • Woon Yong CHOI Dept. of Biomaterials Engineering College of Bioscience and Biotechnology, Kangwon National University, Chunchon 200-701.
  • Yong Chang SEO Dept. of Biomaterials Engineering College of Bioscience and Biotechnology, Kangwon National University, Chunchon 200-701.
  • Ji Seon KIM Dept. of Biomaterials Engineering College of Bioscience and Biotechnology, Kangwon National University, Chunchon 200-701.
  • Choon Geun LEE Dept. of Biomaterials Engineering College of Bioscience and Biotechnology, Kangwon National University, Chunchon 200-701.
  • Do Hyung KANG Marine Living Resources Research Department, Korea Ocean Research & Development Institute, Ansan P.O. Box 29, Seoul 426-744.
  • Hyeon Yong LEE Dept. of Biomaterials Engineering College of Bioscience and Biotechnology, Kangwon National University, Chunchon 200-701.

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