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해양생물공학

Selection of an Optimal Organic Solvent for the Extraction of Prodigiosin

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To develop prodigiosin as biological control agent against Chattonella antiqua, a harmful alga that can cause red tides, selection of an organic solvent for prodigiosin extraction from culture broth was performed.
Prodigiosin was extracted using nine solvents (hexane, toluene, chloroform, ethyl acetate, ethanol, methanol, acetone, acetonitrile, and seawater), and extracts were analyzed by LC-MS. As a result, acetone was regarded as an optimal organic solvent for the extraction of prodigiosin from culture broth. The amount of prodigiosin extracted with acetone was almost the same as that extracted with ethanol.
Moreover, the processing time could be reduced by using acetone because it has a lower boiling point than ethanol. Considering these results, we think that acetone was a very useful extraction agent for the extraction of prodigiosin as a biological control agent. (PE10050 and PN07020).]

저자정보

  • Heeyong PARK Division of life science, Korea Polar Research Institute, Songdo Techno Park, 7-50 Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea.
  • Se Jong HAN Division of life science, Korea Polar Research Institute, Songdo Techno Park, 7-50 Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea.
  • Sung Gu LEE Division of life science, Korea Polar Research Institute, Songdo Techno Park, 7-50 Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea.
  • Joung Han YIM Division of life science, Korea Polar Research Institute, Songdo Techno Park, 7-50 Songdo-dong, Yeonsu-gu, Incheon 406-840, Korea.

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