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논문검색

식품 및 바이오신소재

Immunopotentiating Activity of Sargassum Thunbergii Polysaccharide

원문정보

Eu-Jin SONG, Chung-Jo LEE, Koth-Bong-Woo-Ri KIM, Ji-Yeon JUNG, Min-Ji KIM, Moon Kyung CHOI, Dong-Hyun KIM, Chan SUNWOO, Dong-Hyun AHN

한국생물공학회 한국생물공학회 학술대회 2010 추계학술대회 및 국제심포지움 2010.10 pp.206-206
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

Seaweeds have been attracted recently as multifunctional foods for maintaining human health. So, this study was carried out to verify immune enhancing activities of polysaccharide from Sargassum thunbergii(STP), edible brown seaweeds. Mice (n=5) were orally administered with STP every day for 4 weeks. Peyer’s patch, spleen and peritoneal macrophages were harvested from STP supplemented mice. It was confirmed that the oral administration of 10 and 100 mg/kg.BW STP enhanced proliferation abilities of peyer’s patch cells, splenocytes, and peritoneal macrophages.
The IFN-γ, IL-6 as well as IgA secretion of peyer’s patch cells were significantly increased by STP. In addition, the splenocytes from STP administered mice produced substantially more IFN-γ and peritoneal macrophages secreted more IL-6 and IL-1β compared to PBS administered mice. In conclusion, it is considered that the oral administration of STP could strengthen immune reactions through stimulating an intestinal immunity.

키워드

저자정보

  • Eu-Jin SONG Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Chung-Jo LEE Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Koth-Bong-Woo-Ri KIM Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Ji-Yeon JUNG Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Min-Ji KIM Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Moon Kyung CHOI Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Dong-Hyun KIM Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Chan SUNWOO Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.
  • Dong-Hyun AHN Dept. of Food Science and technology, Pukyong National University, Busan, 608-737.

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자료제공 : 네이버학술정보

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