원문정보
초록
영어
4 kinds of RSNPs(Regional Special Natural Products), Anthrisci Radix, Psoraleae Semen, Siegesbeckiae Herba, Corni Fructus were selected as a anti-obesity subatance through anti-angiogenesis effect. Each natural product inhibited signal pathway such as VEGFR2, or PI3K, or β-catenin or VE-cadherin. And adipogenesis was reduced by 7.5%, 14.4%, 18.3% and 30% at different concentration of Anthrisci Radix when performed Oil red O staining. Also, it was reduced by 2%, 4.9%, 9.3% and 38% at different concentration of Psoraleae Semen. When treated with Siegesbeckiae Herba, it was inhibited by 1.4%, 6.4%, 16.4% and 30.1%, respectively. And Corni
Fructus was also showed by 0.9%, 6.3%, 13.7% and 33% at same concentration of Siegesbeckiae Herba. Also, weight was remarkably reduced by each TSNPs based on reducing triglyceride caused on anti-angiogenesis.