earticle

영어

Paraben preservatives are popular in many cosmetic products but they causes a lot of skin troubles and other harmful effects on human health. In order to replace this paraben compounds, much researches on natural and safe preservatives have been done. In this study, novel organoclays were tested for cosmetic preservatives. The microbial challenge test was
performed followed by USP XXIV method, and CTFA Method M-3 and M-4. The strains used are as follows: E. coli KCTC 1682, Staphylococcus aureus KCTC 1927, Candida albicans IFO No 1594, P. aeruginosa KCTC 2513, Aspergillus niger ATCC 16404, Enteric bacilli, and S. aureus. Organoclays inhibit the bacterial growth from 1% concentration in pH dependent manner. For fungi, there have been no growth inhibition activity. This study shows that 99.99% death of bacteria was observed in 7 days. Thus Mg- and Ca-organoclay could be used as antibiotic
alternatives. Further investigation should be performed to be used as preservation ingredients in cosmetics.