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포스터 발표 : 동물 및 식물세포공학

The Relationship of Differentially Expressed Proteins in Skeletal Muscle and Adipose Tissue between Bull and Steer to Myogenesis and Adipogenesis

원문정보

Qiankun ZHANG, Hong-Gu LEE, Jung-A HANG, Myunggi BAIK, Yun-Jaie CHOI

한국생물공학회 한국생물공학회 학술대회 2010 춘계학술대회 및 국제심포지움 2010.04 pp.198-198
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

The objective of this study was to identify the proteins involved in myogenesis and adipogenesis. Global proteins were monitored in skeletal muscle and adipose tissue between bull and steer, respectively. Through proteomic analysis and comparison, we identified 4 differentially expressed (two-fold or more) proteins from skeletal muscle in steer, down-regulated A, B, C and up-regulated D, and also identified two up-regulated proteins from adipose tissue, E and F. In vitro, after myogenic differentiation of a bovine cell line, the mRNA expression of A, B and D did not changed, but that of C increased significantly (P<0.05). After adipogenic differentiation of a bovine cell line, the mRNA expression of F did not significantly vary, but the expression of E showed about 1.7-fold increase. Therefore, we suggest that C could be indicative
of positive regulator of myogenesis, and E indicative of positive regulator of adipogenesis since they showed a differential expression before and after myogenic and adipogenic differentiation.

키워드

저자정보

  • Qiankun ZHANG Dept. of Agricultural Biotechnology, Seoul National University, Seoul, 151-921.
  • Hong-Gu LEE Dept. of Animal Science and PNU-Special Animal Biotechnology Center, Pusan National University, Gyeongnam 627-706.
  • Jung-A HANG Dept. of Agricultural Biotechnology, Seoul National University, Seoul, 151-921.
  • Myunggi BAIK Dept. of Applied Bioscience and Biotechnology, Chonnam National University, Kwangju 500-757.
  • Yun-Jaie CHOI Dept. of Agricultural Biotechnology, Seoul National University, Seoul, 151-921.

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자료제공 : 네이버학술정보

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