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This research was performed to determine the antioxidant activities, angiotensin converting enzyme (ACE) inhibitory effect, alcohol metabolizing activities, and nitrite scavenging activity of aga-oligosaccharides. Antioxidant activities were measured by using 2,2-diphenyl-1-picryl-hydrazyl (DPPA) free radical scavenging activity and super oxide dismutase (SOD) activity.
DPPH radical scavenging activity and SOD activity of aga-oligosaccharides were remarkably increased in a dose-dependent manner and was about 64.31% at 1 mg/ml and 82.1% at 0.2 mg/ml. The ACE inhibitory activity of aga-oligosaccharids ware also increased in a dose-dependent manner. To determine the influence of aga-oligosaccharids on alcohol metabolism, the generating activites of reduced-nicotinamide adenine dinucleotide (NADH) by alcohol dehydrogenase (ADH) and acetaldehyde dehydrogenase (ALDH) were measured. Facilitating rates of ADH activity by aga-oligosaccharids ware 121.6% at 0.4 mg/ml and ALDH activity was 104.5% at 1 mg/ml. Nitirite scavenging activity, which was measured at various pH conditions(1.2,3.0,6.0) was about 95.8% at 1 mg/ml and pH 1.2. These results revealed that agaoligosaccharides have a strong antioxidant activity alcohol metabolizing activity, antioxidant activity and ACE inhibitory activity.