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포스터 발표 : 식품 및 바이오신소재

Anti-inflammatory A ctivity of Pine pollen, Pine needle and Pine gnarl Ethanol Extractsin LPS-Stimulated Murine Macrophages

원문정보

Chung-Jo LEE, Eu-Jin SONG, Koth-Bong-Woo-Ri KIM, Na-Bi PARK, Ji-Yeon JUNG, Ji-Hee KWAK, Moon-Kyung CHOI, Min-Ji KIM, Tae-Wan KIM, Dong-Hyun AHN

한국생물공학회 한국생물공학회 학술대회 2010 춘계학술대회 및 국제심포지움 2010.04 pp.168-168
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

Recently, many investigators have initiated searches for anti-inflammatory substances from natural resources because of an increasing trend in various inflammatory diseases. The pine (Pinus densiflora) is one of the popular plant drugs which have been used as a medicine in Asia.
Therefore, we studied anti-inflammatory activity of ethanol extracts from different parts of pine in LPS-stimulated murine macrophages. As a result, nitric oxide (NO) production of pine pollen (PP) and pine needle (PN) ethanol extracts was lower than the control at a concentration of
50 μg/mL, while NO production of pine gnarl (PG) ethanol extracts made no considerable differences. Also, TNF-α, IL-6 and IL-1β levels decreased in PP, PE and PG ethanol extracts at the concentration of 1-50 μg/mL. Especially, PE ethanol extracts showed the lowest TNF-α,
IL-6 and IL-1β levels at a concentration of 50 μg/mL. In conclusion, it is demonstrated that PP, PE and PG ethanol extracts have anti-inflammatory activity in LPS-stimulated murine macrophages.

키워드

저자정보

  • Chung-Jo LEE Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Eu-Jin SONG Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Koth-Bong-Woo-Ri KIM Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Na-Bi PARK Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Ji-Yeon JUNG Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Ji-Hee KWAK Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Moon-Kyung CHOI Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Min-Ji KIM Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.
  • Tae-Wan KIM Dept. of Food Science & Biotechnology, Andong National University, Gyeongbuk 760-749.
  • Dong-Hyun AHN Dept. of Food Science & Technology, Pukyong National University, Busan 608-737.

참고문헌

자료제공 : 네이버학술정보

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