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An astaxanthin is a red pigment in carotenoid to have the economic value about ~$2000 per kilo of pure astaxanthin. And the micro-alga Haematococcus pluvialis is not only to date recognized as the organism to accumulate the highest levels of astaxanthin in nature but also able to dispose of the GHG (green house gas) through the CO2 assimilation by photosynthesis. But this phenomenon is physiologically based on the well-separated system of life cycle in H. pluvialis between a growth and an induction phase. Consequently, the growth of this organism should be
always arrested by unknown factors from the ROS (reactive oxygen species) response mechanism to produce an astaxanthin. To improve both the growth and astaxanthin production of H. pluvialis, variable random techniques of mutagenesis were attempted by investigators with
many kinds of inhibitors. But it showed the relationship between the growth and astaxanthin production levels was generally inversed. From this point of view, various biocompatible organic and inorganic compounds are tested to improve the two parameters together by increasing the CO2 fixation rate of H. pluvialis.