earticle

영어

Mussel adhesive proteins (MAPs), found in byssal adhesive plaques, have come to be recognized as very attractive biomaterials thanks to their fascinating thanks to their fascinating properties including strong and flexible adhesion in any substrates in wet environments. Especially, MAP fp-5 from the highest 3,4-dihydroxyphenyl-L-alanine (DOPA) content is mainly involved in binding, serving as a adhesive between a surface and the adhesion plaque of mussels. However, it has been very difficult to obtain purified natural MAP fp-5 in quantity. In this study, we firstly over-expressed Mytilus galloprovincialis-originated fp-5 in Escherichia coli and efficiently purified the protein. Mechanical properties of fp-5 was investigated, and multi-functional coatings were formed through simple dip-coating of objects in a fp-5 aqueous solution.
From this study, we expect MAP fp-5 can be used as a significant bioadhesive and an efficient multi-functional surface coating material.