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The purpose of this study was to investigate the responses of an acute resistance exercise of 60% one repetition maximum (60% 1RM) and aerobic exercise of 60% heart rate reserve maximum (60% HRRmax) to anabolic hormones, lipase, CK. We also tried to look for the information regarding the relation of anabolic hormones, enzymes to exercise rehabilitation. The subjects consisted of 10 healthy young men. They were set to practice 2 exercise types (aerobic exercise of 60% HRRmax and resistance exercise of 60% 1RM) at an interval of a week for 60 minutes (including 10 minutes of warm-up and 10 minutes of cool-down). Blood was sampled 3 times (rest, immediately after exercise, 60 minutes after exercise) and then analyzed for the reaction of growth hormone, testosterone, lipase and creatine kinase (CK) to exercise types. The results are as follows. First, there was no significant difference between the responses of an acute aerobic exercise of 60% HRRmax and resistance exercise of 60% 1RM to anabolic hormones, lipase. Second, resistance exercise with 60% 1RM showed a quicker effect on early secretion of growth hormone than aerobic exercise of 60% HRRmax. Third, when compared with the levels at rest and immediately after exercise, the stimulation of aerobic exercise with 60% HRRmax and resistance exercise with 60% 1RM 60 minutes after exercise reduced lipase activity significantly. Fourth, when compared with resting levels, CK activity was reduced significantly immediately after exercise and was recovered at 60 minutes after exercise to rest level. However, when compared with rest, resistance exercise of 60% 1RM reduced CK activity at immediately after exercise and 60 minutes after exercise. Therefore, resistance exercise showed a more harmful effect on tissue damage than aerobic exercise. In summary, these results indicate that the effect of an acute aerobic exercise of 60% HRRmax and resistance exercise of 60% 1RM on the reduction of lipase activity at 60 minutes after exercise are related to the reduction of anabolic hormones at 60 minutes after exercise. This result also showed that the reduction of anabolic hormones at 60 minutes after resistance exercise was related to the high levels of CK activity at 60 minutes after exercise. Therefore, these results indicate that both of an acute aerobic exercise of 60% HRRmax and resistance execise of 60% 1RM in healthy young men have effects on growth hormone, testosterone, lipase and GK. This study also suggests that relatively low intensity of aerobic- and resistance exercise may play an important role in the prescription for exercise rehabilitation regarding both of healthy and weak person.