원문정보
초록
영어
Whole-body vibration exercise is a new type of exercise currently being tested in rehabilitation and that recently been developed for the prevention and treatment of osteoporosis[1, 2]. But most research in this field has been limited to osteogenesis and has focused on intervertebral disc degeneration. The aim of this study is to investigate the influence of lipolysis on matured 3T3-L1 cells by sonic vibration for 6 days. Cultured 3T3-L1 cells were subjected to sonic vibration 1 h
treatment 3 times per day on an apparatus which was used sonic vibration with 3.5 and 5.1 volt and the frequency was the 50 Hz. The total TG (triglyceride) content of cells was similar compared with the control. But in the experiments of lipolytic activity, glycerol secretion was increased with the rates of approximately 59% and 60% at the intensity of 3.5 and 5.1 volt respectively. HSL (hormone-sensitive lipase) has traditionally been considered the key lipolytic enzyme in adipocytes[3].The gene expression levels of HSL was increased by using RT-PCR. In conclusion, treatment of sonic vibration inhibits adipogenesis through recduction in lipid accumulation.