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영어
Anticancer activities of Spirulina maxima extracts under three different conditions (EtOH at 80℃, water at 100℃, and ultrasonification at 60℃) were examined. Their extraction yields were 10.3%, 19.8%, and 33.46%, respectively. Cell differentiation of HL-60 cell was greatly accelerated up to 170% in adding 0.5 mg/ml of ultrasonification extracts. On the other hand, EtOH extract showed the lowest differentiation as 125%. It indicates that Spirulina maxima would have anticancer effects by showing the increasing tendency of extinction mechanism. Compared to the control group, B cell lymphoma-2(Bcl-2) expression from HL-60 was estimated as 96(IOD) in adding the
extracts from ultrasonification, which can tell that this extracts would work out inhibity the latter parts of cancer cell transmission. Therefore, the ultrasonification extract of S. maxima can be used as one of anticancer resources after further analysis and purification.