원문정보
초록
영어
Berberis koreana bark was fermented by Lactobacillus paracasei(L.P) and Bifidobacterium longum B6(B.L) for improving its antioxidant and tyrosinase inhibition activity. Extraction yields of the crude extracts and fermented extracts were 5.32% and 11.52%, respectively. It was found that the fermentation process greatly improved the extraction yield of hard woods. The cytotoxicity of all the fermented extracts on human fibroblast cell line(CCD986SK) was low as 15%, which was lower than the crude extracts as 16-25%. Tyrosinase activity was inhibited as 20.1% and 26.04% for crude extract and fermented extracts, respectively. Antioxidant activity was also evaluated as fellows: for DPPH radical scavenging, highest activity was observed in fermented
extracts as 65.4% at 1mg/ml concentration. For SOD-like test, fermented extracts as 31.9% at 1mg/ml concentration. The total phenol contents in the fermented extracts was increased up to 10 ppm by ultrasonifiction extraction. The result, fells that the bark of Berberis koreana can be
considered as a candidate of new functional cosmetic agents by employing the fermentation process.