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논문검색

식품 및 바이오신소재

Immune enhancing activity of Eckloia stolonifera water extract

원문정보

Song EU-JIN, Lee CHUNG-JO, Lee SO-YOUNG, Kim KOTH-BONG-WOO-RI, Yoon SO-YOUNG, Lee SO-JEONG, Jung JI-YEOON, Park NA-BI, Kwak JI-HEE, Ahn DONG-HYUN

한국생물공학회 한국생물공학회 학술대회 2009 추계학술대회 및 국제심포지움 2009.11 pp.200-200
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

Seaweeds have been attracted recently as multifunctional foods for maintaining human health. So, this study was carried out to verify the innate and adaptive immune enhancing activity of Ecklonia stolonifera, edible brown seaweeds, water extract (ESWE). ESWE was added to
macrophages and splenocytes obtained from Balb/c mice. After then, NO production and TNF-α, IL-6, and IL-1β levels in macrophages were measured. Cell proliferation and IFN-γ and IL-2 levels in splenocytes were also determined. As a result, it was confirmed that ESWE
increased NO produced from activated macrophages for removing invaded bacterial at the concentration of 1-100 μg/mL. Also, pro-inflammatory cytokines, TNF-α, IL-6, and IL-1β, levels in macrophages were enhanced when ESWE was added. For splenocytes, ESWE boosted
IFN-γ secretion at the concentration of 0.1-100 μg/mL while IL-2 secretion was increased at 0.1 μg/mL only. In addition, it was founded that ESWE considerably stimulated the cell proliferation at all tested concentration. In conclusion, it is considered that ESWE could strengthen
both innate and adaptive immunity.

키워드

저자정보

  • Song EU-JIN Department of Food Science and technology, Pukyong national university
  • Lee CHUNG-JO Department of Food Science and technology, Pukyong national university
  • Lee SO-YOUNG Department of Food Science and technology, Pukyong national university
  • Kim KOTH-BONG-WOO-RI Department of Food Science and technology, Pukyong national university
  • Yoon SO-YOUNG Department of Food Science and technology, Pukyong national university
  • Lee SO-JEONG Department of Food Science and technology, Pukyong national university
  • Jung JI-YEOON Department of Food Science and technology, Pukyong national university
  • Park NA-BI Department of Food Science and technology, Pukyong national university
  • Kwak JI-HEE Department of Food Science and technology, Pukyong national university
  • Ahn DONG-HYUN Department of Food Science and technology, Pukyong national university

참고문헌

자료제공 : 네이버학술정보

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