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식품 및 바이오신소재

Immunomodulating Activity of Myagropsis myagroides Water Extract on Murine Splenocytes and Macrophages

원문정보

Chung-Jo LEE, Eu-Jin SONG, Ji-Hee KWAK, So-Young LEE, Koth-Bong-Woo-Ri KIM, So-Young YOON, So-Jeong LEE, Na-Bi PARK, Ji-Yeon JUNG, Gi-Wan NAM, Dong-Hyun AHN

한국생물공학회 한국생물공학회 학술대회 2009 추계학술대회 및 국제심포지움 2009.11 pp.195-195
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

We investigated that Myagropsis myagroides water extract (MMWE) has immunological effect on murine splenocytes and macrophages in vitro. As a result, MMWE enhanced the splenocytes proliferation at all concentrations without cytotoxicity. Also, the IFN-γ secreation of
MMWE treated group increased at the concentration of 0.1~10 μg/mL, whereas the IL-2 secreation increased at the concentration of 0.1~1 μg/mL. Nitric oxide production on macrophages treated with MMWE was higher than PBS treated group. The IL-6 and IL-1β levels were enhanced on macrophages treated with MMWE, while the TNF-α secreation makes a no difference both PBS and MMWE treated group. In conclusion, MMWE showed a substantial immunomodulating activity on the murine immune cell.

키워드

저자정보

  • Chung-Jo LEE Dept. of Food Science and Technology, Pukyong National University
  • Eu-Jin SONG Dept. of Food Science and Technology, Pukyong National University
  • Ji-Hee KWAK Dept. of Food Science and Technology, Pukyong National University
  • So-Young LEE Dept. of Food Science and Technology, Pukyong National University
  • Koth-Bong-Woo-Ri KIM Dept. of Food Science and Technology, Pukyong National University
  • So-Young YOON Dept. of Food Science and Technology, Pukyong National University
  • So-Jeong LEE Dept. of Food Science and Technology, Pukyong National University
  • Na-Bi PARK Dept. of Food Science and Technology, Pukyong National University
  • Ji-Yeon JUNG Dept. of Food Science and Technology, Pukyong National University
  • Gi-Wan NAM Dept. of Marine Biology, Pukyong National University
  • Dong-Hyun AHN Dept. of Food Science and Technology, Pukyong National University

참고문헌

자료제공 : 네이버학술정보

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