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Crucial Roles of Snf1 Kinase in Tolerance of Saccharomyces cerevisiae against Fermentation Inhibitors from Lignocellulosic Biomass

초록

영어

Budding yeast Saccharomyces cerevisiae plays an important role in producing bioethanol from lignocellulosic biomass. Pretreatment of lignocellulosic biomass releases a number of inhibitors reducing cell growth and ethanol production, which suggests an elaborate research
should be performed to increase resistance of S. cerevisiae against fermentation inhibitors. Sucrose non-fermenting 1 (Snf1) is an AMPactivated serine/threonine protein kinase in yeast and is an important kinase for metabolic and developmental response in S. cerevisiae.
Phenotypes of snf1 null mutant of S. cerevisiae on inhibitor-containing medium clearly indicated that Snf1 kinase plays crucial roles in tolerance of S. cerevisiae against fermentation inhibitors, which can be used as useful milestone for development of economically feasible
bioethanol production process using yeast, S. cerevisiae.

저자정보

  • Eun-Hee PARK School of Bioscience and Biotechnology, and K-Medicon Center, Kangwon National University
  • Ha-Yeon LEE School of Bioscience and Biotechnology, and K-Medicon Center, Kangwon National University
  • Da-Hye KIM School of Bioscience and Biotechnology, and K-Medicon Center, Kangwon National University
  • Jin-Ho SEO Department of Agricultural Biotechnology, Seoul National University
  • Kyung-Heon KIM School of Life Sciences and Biotechnology, Korea University
  • Myoung-Dong KIM School of Bioscience and Biotechnology, and K-Medicon Center, Kangwon National University

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