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Drug delivery technologies have developed into innovative platforms that will make impacts for the pharmaceutical industry in every therapeutic category. Recently, the applications of drug delivery technologies are enormous, offering big opportunities to cure diseases more effectively than ever before. Drug delivery systems can advanced a product’s medicinal value by enhancing
pharmacological improvement over conventional products on the market. And also, the right drug delivery system can raise a product’s market value by improving side-effects, tolerability and compliance issues. Drug delivery technologies have also used as a tool extending a product’s life cycle management with high profitability. Developing new and improved pharmaceuticals
with drug delivery technologies has giving opportunity to pharmaceutical company’s key products which face patent expiration, for expending product life and sustaining value- added products. The advanced drug delivery technologies are including extended- release oral formulations, organ specific target, ,transdermal patches, topical creams, nasal spray, etc. For example, almost all therapeutic proteins are delivered by intravenous, subcutaneous, or intramuscular injection. A major reason for better protein delivery is needed is that patients do not like needles, especially when frequent injections are needed for treating chronic diseases. Fear and dislike of syringes is freighted with implications for compliance and health costs. Oral delivery is unquestionably the most popular form of drug delivery administration. Injection are probably the least. Today, bioavailability rarely reaches 1% when therapeutic peptides and proteins are taken orally. .If one can develop a new technology to have with over 10% bioavailability if oral protein delivery, it will be a great success for the market. The contents of this presentation will be reported the progress of “Development of controlled drug delivery system” supported by the Ministry of Knowledge and Economy (MKE) and 5 different companies for 5 years project. The program is composed by 5 subprojects as (1) development of novel osmotic pump, (2) liposome delivery system for anti tumor , (3) drug delivery system by bile acid
transporter for oral delivery of antibiotics, (4)protein delivery of system using thermo-sensitive hydrogel, and (5) novel transdermal drug delivery system for anti-inflamation.