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Research Articles

Synergistic Effects of KH-red Ginseng/chlorella on the Endurance Capacity and Immune Enhancing in Forced Swimming Tested Mice

초록

영어

KH-red ginseng/chlorella (KH-RG/C) is the mixed material of the Korean red ginseng powder (Panax ginseng, 75%) and extract of Chlorella vulgaris (25%). To evaluate the effects of KH-RG/C on endurance capacity and immune regulation, the forced swimming test (FST) was conducted. The immobility time in the FST was significantly decreased in KH-RG/C treated group compared with the DW-treated group at the 3 and 10 days, respectively. In the analysis of the blood biochemical parameters, KH-RG/C treatment significantly increased the glucose level. However, the lactic dehydrogenase level decreased. Although KH-RG/C increased aspartate aminotransferase, it was not different significantly. And KH-RG/C had no affects in the alanine aminotransferase, and blood urea nitrogen levels. In splenocytes and macrophages, KH-RG/C
also did not affect the interleukin (IL)-2, IL-4, and IL-12 production. These results suggest that KH-RG/C may influence to immune regulation through increasing the physical endurance capacity without effect in activation of immune cells.

목차

Abstract
 Introduction
 Materials and Methods
 Results and Discussion
 References

저자정보

  • In-Young Choi Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Ji-Hyun Lee Department of Pharmacology, College of Pharmacy, Wonkwang University
  • Tae-Hee Kang Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Hyo-Jin An Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Su-Jin Kim Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Phil-Dong Moon Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Na-Hyung Kim Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Noh-Yil Myung Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Deok-Chun Yang Department of Oriental Medicine Material and Processing, College of Life Science, Kyung Hee University
  • In-Cheol Kang Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Youngjin Choi Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Min-Ho Kim NUMATE of Chonbuk National University
  • Jae-Young Um Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Seung-Heon Hong Department of Pharmacology, College of Pharmacy, Wonkwang University
  • Hyung-Min Kim Department of Pharmacology, College of Oriental Medicine, Institute of Oriental Medicine, Kyung Hee University
  • Hyun-Ja Jeong Biochip Research Center, Hoseo University

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