earticle

영어

Water extracts of injinssuk (Artemisia iwayomogi Kitamura) (WE) were obtained from the dried and ground leavesand stems of injinssuk. The WE was further fractionated into crude polysaccharide (C-PS) and nonpolysaccharide fractions(N-PS). The protective activities against the tert-butyl hydro peroxide induced mutangenecity on Escherichia coli PQ37 andreactive oxygen species scavenging activity of the WE, C-PS, and N-PS were studied. The WE obtained from leaves showeda significantly higher inhibitory effect on the mutagenicity than WE from stem. The WE obtained from the leaves havinghigher crude polysaccharide content but lower content of total carbohydrates had significantly higher antimutagenicity thanthat from the leaves with lower crude polysaccharide but higher total carbohydrate contents. Further study showed that C-PSfraction showed markedly stronger antimutagenic effect than N-PS. C-PS was also more effective than N-PS for hydroxylradical scavenging activity, but was similar to N-PS in superoxide radical scavenging activity.