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RESEARCH REVIEW

Applications of Capillary Electrophoresis and Microchip Capillary Electrophoresis for Detection of Genetically Modified Organisms

원문정보

Guonan Chen, Longhua Guo, Bin Qiu, Xueyang Xiao

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초록

영어

In recent years, special concerns have been raised about the safety assessment of foods and food ingredientsderived from genetically modified organisms (GMOs). A growing number of countries establish regulations and laws forGMOs in order to allow consumers an informed choice. In this case, a lot of methods have been developed for the detection ofGMOs. However, the reproducibility among methods and laboratories is still a problem. Consequently, it is still in greatdemand for more effective methods. In comparison with the gel electrophoresis, the capillary electrophoresis (CE) technologyhas some unique advantages, such as high resolution efficiency and less time consumption. Therefore, some CE-basedmethods have been developed for the detection of GMOs in recent years. All kinds of CE detection methods, such asultraviolet (UV), laser induced fluorescence (LIF), and chemiluminescence (CL) detection, have been used for GMOsdetection. Microchip capillary electrophoresis (MCE) methods have also been used for GMOs detection and they have shownsome unique advantages.

목차

Abstract
 Introduction
 CE-based Methods for the Detection of ExogenousDNA in GMOs
 CE-based Methods for the Detection of Proteinsand Metabolites of GMOs
 Applications of MCE for the Detection of GMOs
 Conclusions and Prospects
 References

저자정보

  • Longhua Guo Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou 350002, PR China
  • Bin Qiu Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou 350002, PR China
  • Xueyang Xiao Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou 350002, PR China
  • Guonan Chen Ministry of Education Key Laboratory of Analysis and Detection Technology for Food Safety (Fuzhou University), Department of Chemistry, Fuzhou University, Fuzhou 350002, PR China

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