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RESEARCH REVIEW

Bioactivities and Potential Mechanisms of Action for Conjugated Fatty Acids

원문정보

Yeonhwa Park, Michael W. Pariza

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초록

영어

Since conjugated linoleic acid (CLA) was identified as a principal anticancer component from ground beef in the1980s, CLA research has discovered that CLA has a wide range of biologically beneficial effects. Clinical studies with CLAare on the rise, and it is apparent that CLA may not be as effective in humans as in rodents, in particular its anti-obesity aspect.In addition, research with regard to other conjugated fatty acids as well as CLA metabolites is still in its infancy. Investigationof bioactivities for other conjugated fatty acids and CLA metabolites may help to extend the understanding of CLA and itsmechanisms of actions. This may pose an opportunity to use CLA more efficiently and expand the future use of otherconjugated fatty acids as pharmacological agents to assist current treatments.

목차

Abstract
 Introduction
 Origins of CLA
 Biological Activities of CLA
 CLA Isomer Interaction
 Safety Issues
 Other Conjugated Fatty Acids
 Conclusion
 References

저자정보

  • Yeonhwa Park Department of Food Science, University of Massachusetts, Amherst, 100 Holdsworth Way, Amherst, MA 01003, USA
  • Michael W. Pariza Food Research Institute, University of Wisconsin-Madison, 1550 Linden Dr., Madison, WI 53706, USA

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