earticle

영어

Inhibitory effect of Escherichia coli O157 adhered to Caco-2 cells by the cells of Lactobacillus plantarum K11and the cell-free culture supernatant (CFCS) and bacteriocin prepared from this strain was investigated. As the cell counts ofviable L. plantarum K11 previously adhered to Caco-2 were increased, the rate of adhesion and adherent cell counts of E. coliO157 was lower. However, because the heated L. plantarum K11 rarely have the adhesion ability to Caco-2, the adhesion rateand adherent cell counts of E. coli O157 were high. In addition, the inhibitory effects of E. coli O157 adhesion by the CFCSand bacteriocin of L. plantarum K11 were dose-dependent manner. Therefore, the inhibition of adhesion of E. coli O157 toCaco-2 may result from the antimicrobial substances such as lactic acid and bacteriocin. Moreover the inhibitory activity ofadhesion by the heated bacteriocin for 30min at 100oC was similar to activity of non-treated bacteriocin, but the activity wasdisappeared by treatment with protease.