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논문검색

바이오의약 및 약물전달 분야

Selection of Anti-Obesity Materials from Regional Natural Products Based on Anti-Angiogenesis Model

원문정보

Jong Deog KIM, Jin Hyuk SHIN, Go Un CHAE, Seung Cheol BAEK, Jin Hee LEE, Kyeong Hwan KANG, Jae Ho WHANG, Kyeong Ho HAN, Tai Sun SHIN, Suk Jung OH, Min Yong KIM

한국생물공학회 한국생물공학회 학술대회 2009 춘계학술대회 및 국제심포지움 2009.04 pp.203-203
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

10 kinds of natural products bearing anti-angiogenesis and anti-obesity were selected through tube formation and RT-PCR. For verifying the mechanism of anti-angiogenesis, forward and reverse primers of signal molecules such as VEGFR2, PI3K, β-catenin, VE-cadherin were
constructed based on NCBI data base. Agarose gel bands showed antiangiogenic effect through variation of signal molecule with increasing concentration of natural products. Also, SREBP-1c, PPARγ and C/EBPα protein which stimulate lipogenesis and adipogenesis were experimented for controlling effect by selected natural products.

키워드

저자정보

  • Jong Deog KIM Department of Biotechnology, Research center on Anti-Obesity and Health Care, Chonnam National University
  • Jin Hyuk SHIN Department of Biotechnology, Chonnam National University
  • Go Un CHAE Department of Biotechnology, Chonnam National University
  • Seung Cheol BAEK Department of Biotechnology, Chonnam National University
  • Jin Hee LEE Dept. of Culture Biotechnology, Chonnam National University
  • Kyeong Hwan KANG Dept. of Culture Biotechnology, Chonnam National University
  • Jae Ho WHANG Dept. of Culture Biotechnology, Chonnam National University
  • Kyeong Ho HAN Dept. of Culture Biotechnology, Chonnam National University
  • Tai Sun SHIN Food Science and Nutrition, Chonnam National University
  • Suk Jung OH TBI center, Chonnam Univ,
  • Min Yong KIM Dept. of Refrigeration Eng., ChonnamNational University

참고문헌

자료제공 : 네이버학술정보

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