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논문검색

바이오의약 및 약물전달 분야

Verifying the Mechanism of Anti-Angiogenesis for Anti-Obesity

원문정보

Jong Deog KIM, Jin Hyuk SHIN, Ji Un CHEONG, Jin Hee LEE, Kyeong Hwan KANG, Jae Ho WHANG, Kyeong Ho HAN, Tai Sun SHIN, Min Yong KIM

한국생물공학회 한국생물공학회 학술대회 2009 춘계학술대회 및 국제심포지움 2009.04 pp.203-203
피인용수 : 0건 (자료제공 : 네이버학술정보)

초록

영어

4 kinds of natural product, Anthrisci Radix, Psoraleae Semen, Siegesbeckiae Herba, Corni Fructus were selected as a anti-obesity subatance through anti-angiogenesis effect. Each natural product inhibited signal pathway such as VEGFR2, or PI3K, or β-catenin or VE-cadherin, and all 4 kinds of selected natural products prohibit Akt signal molecule which is down-located thanVEGFR2, PI3K, β-catenin and VE-cadherin. Therefore 4 kinds of natural product can supress signal to NF-kB for not occuring angiogenesis.

키워드

저자정보

  • Jong Deog KIM Department of Biotechnology, Research center on Anti-Obesity and Health Care, Chonnam National University
  • Jin Hyuk SHIN Department of Biotechnology, Chonnam National University
  • Ji Un CHEONG Department of Biotechnology, Chonnam National University
  • Jin Hee LEE Dept. of Culture Biotechnology, Chonnam National University
  • Kyeong Hwan KANG Dept. of Culture Biotechnology, Chonnam National University
  • Jae Ho WHANG Dept. of Culture Biotechnology, Chonnam National University
  • Kyeong Ho HAN Dept. of Culture Biotechnology, Chonnam National University
  • Tai Sun SHIN Food Science and Nutrition, Chonnam National University
  • Min Yong KIM Dept. of Refrigeration Eng., Chonnam National University

참고문헌

자료제공 : 네이버학술정보

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