earticle

논문검색

바이오센서 및 바이오칩 분야

Nanobio-Device for Label-Free Dtection of Biological Interactions

초록

영어

We developed a simple method for fabrication of nanometer distance gap (nanogap). The size of the nanogap was controlled by adjusting the dimension of the window mask and finally the nanogap having a width less than 60 nm was obtained. Furthermore, we used the nanogap for electrical biosensing of biomolecular interaction without labeling. The current was proportionally increased to the concentrations of the charged molecules in the range from 100 fg/ml to 100 ng/ml at 1 V bias. It is expected that the nanogap developed here can be used as a biosensor platform for label-free detection of biomolecular interactions.

저자정보

  • Sang Kyu KIM BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, P.O.Box 115, Yuseong, Daejeon 305-600.
  • Hyunmin CHO BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, P.O.Box 115, Yuseong, Daejeon 305-600.
  • Bong Hyun CHUNG BioNanotechnology Research Center, Korea Research Institute of Bioscience and Biotechnology, P.O.Box 115, Yuseong, Daejeon 305-600.

참고문헌

자료제공 : 네이버학술정보

    함께 이용한 논문

      ※ 원문제공기관과의 협약기간이 종료되어 열람이 제한될 수 있습니다.

      0개의 논문이 장바구니에 담겼습니다.