earticle

영어

Nanosurface consisting of nano structures was developed to enhance the surface density of capture protein on spot in protein chip array. Silica nano pillar was formed from nanoporous alumina template using sol-gel method. Silica nano pillars were transferred to PDMS layer
prior to remove the alumina template. Silica nano structure was achieved with individual pillars by their aggregations because they have high aspect ratio (length: 1000 nm, diameter: 80 nm). Nano structure has 600 nm of height and 1000 nm of diameter. The rose’s petal effect was achieved with nanosurface because nanostructure contains individual nano pillars. Nanosurface consisting of nanostructures was investigated using AFM（Atomic Force Microscopy) and SEM
(Scanning Electron Microscopy). The amount of protein immobilized on nanosurface was compared with that on normal flat glass. Nanosurface developed in this study can be applied to nanoscaled biochip. Acknowledgments: This work was supported by the Korea Science and Engineering Foundation (KOSEF) grant funded by the Korea government (MOST) (No. M10755160002-07N5516-00210).